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Galaxy HiCExplorer: a web server for reproducible Hi-C data analysis, quality control and visualization


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HiCExplorer - a tool suite for reproducible Hi-C data analysis, quality control and visualization was published a few days ago.

Thanks to this amazing team!

Graphical abstract for Galaxy HiC Explorer

We even made it on the Cover of the latest Nucleic Acids Research Webserver issue.

Abstract

Galaxy HiCExplorer is a web server that facilitates the study of the 3D conformation of chromatin by allowing Hi-C data processing, analysis and visualization. With the Galaxy HiCExplorer web server, users with little bioinformatic background can perform every step of the analysis in one workflow: mapping of the raw sequence data, creation of Hi-C contact matrices, quality assessment, correction of contact matrices and identification of topological associated domains (TADs) and A/B compartments. Users can create publication ready plots of the contact matrix, A/B compartments, and TADs on a selected genomic locus, along with additional information like gene tracks or ChIP-seq signals. Galaxy HiCExplorer is freely usable at: https://hicexplorer.usegalaxy.eu and is available as a Docker container: https://github.com/deeptools/docker-galaxy-hicexplorer.

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